General Spectrum of Activity
Targeted therapy of resistant gram-positive infections with MRSA (particularly when vancomycin MIC≥2) and VRE including endovascular infection.
Creatine kinase weekly.
Statins and fibrates - Increased myopathy.
Monitor creatine kinase while on daptomycin therapy.
Antimicrobial class: Cyclic Lipopeptide
Pregnancy category: B
Average serum half life: 9 hours
Urine penetration: Therapeutic
Lung penetration: Inactivated by surfactant
CSF penetration: Poor