General Information

Anaerobic infections above the diaphragm, especially dental infection.

Gram positive skin and soft tissue infections including necrotizing fasciitis as an adjunctive agent to a beta lactam for reducing toxin production.

Skin & soft tissue infections involving susceptible MRSA.

Susceptible infections and surgical prophylaxis in setting of IgE mediated beta-lactam allergy.

For decreasing toxin production in toxic shock syndrome.

  • Diarrhea
  • C. difficile

Muscle relaxants (e.g. atracurium, baclofen, diazepam).

St. Johns Wort.

Medication cost calculated per day (24 hours) of therapy for the average adult dose (70kg) of 300mg PO q6h or 600mg IV q8h.

Antimicrobial class: Lincosamide

Pregnancy category: B

Average serum half life: 2.4 hours

Urine penetration: Poor

Lung penetration: Therapeutic

CSF penetration: Poor

Biliary penetration: Therapeutic