General Spectrum of Activity
H. pylorI and mycobacterial infections
Monitor QTc in patients with increased risk.
Prolongation of QTc interval
Recommend review of patient medications due to high frequency of significant interactions.
Very high tissue penetration and concentration intracellularly means in vivo activity may not be predicted by in vitro testing.
Antimicrobial class: Macrolide
Pregnancy category: C
Average serum half life: 5 hours
Urine penetration: Poor
Lung penetration: Therapeutic
CSF penetration: Poor
Biliary penetration: Therapeutic