General Spectrum of Activity
Restricted to use in gram-negative infections (no gram positive coverage) where no prior beta-lactams have been tolerated and patient has a severe PCN or cephalosporin allergy.
Monitor liver enzymes.
No significant interactions.
Cost based on dose of 1g IV q8h.
Antimicrobial class: Monobactam
Pregnancy category: B
Average serum half life: 2 hours
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Therapeutic only when meninges inflamed
Biliary penetration: Therapeutic