Contact Precautions
If any visible skin vesicles
Diagnostic Recommendations
Consult ID
CSF for cell count, and HSV PCR
Other testing to be done in consultation with microbiology or ID
For other etiology specific treatment, consult ID
HSV
Acyclovir
Neonatal HSV Encephalitis: 21 days IV plus 6 months of suppressive therapy with oral acyclovir
Infants and Older Children with HSV Encephalitis: 21 days IV therapy. Repeat CSF recommended to document a negative PCR prior to discontinuing acyclovir
References
IDSA Guideline, Herpes Simplex Virus-1 Encephalitis, 2012 Available Here