Moderate
CrCl ≥60 mL/minute
- There are no dosage adjustments provided in the manufacturer's labeling
Severe
Avoid if CrCl <30 ml/min
- Limited data suggest nitrofurantoin is safe and effective for short-term treatment of uncomplicated urinary tract infection (UTI) in patients with CrCl 30 to 60 mL/minute
