Regular monthly ophthalmic exams recommended in patients receiving >15 mg/kg/day. Use with caution in children in whom visual acuity cannot be monitored (generally <5 years of age).
Ethambutol, 15 mg/kg/day is the preferred dosage as there is less risk of optic neuritis. At this dose, ethambutol is bacteriostatic, but will help prevent the development of resistance. It is bactericidal at a dose of 25 mg/kg/day.