>6 months15 mg/kg/dose PO q12h Dose limit: 1 g/day
≥2 years7.5 mg/kg/dose PO q12h
Severe: Reduce dose by 50%
Otitis media, pharyngitis/tonsilitis
ODB Funded (tablets, oral liquid)
1% to 10%:
Central nervous system: Dizziness (1%)
Dermatologic: Diaper rash (2%), genital pruritus (2%)
Gastrointestinal: Nausea (4%), diarrhea (3%), abdominal pain (1%), vomiting (1%)
Genitourinary: Vaginitis
Hepatic: Increased serum transaminases (2%)
Infection: Superinfection
Evaluate renal function before and during therapy
With prolonged therapy, monitor coagulation tests, CBC, and liver function tests periodically
Monitor for signs of anaphylaxis during first dose
Food delays cefprozil absorption
Management: May administer with food
Should be used as a 2nd line alternative to cefuroxime axetil