TreatmentTick Bite Prophylaxis2 mg/kg/dose PO q12h for 14 days Dose limit: 100 mg/dose4.4 mg/kg/dose PO once as a single dose, initiate within 72 hours of tick removal Dose limit: 200mg/dose- Prophylaxis with a single dose of doxycycline for tick bites can be considered if the tick was engorged, tick was attached >36 hours, and prophylaxis is given within 72 hours of tic removal
InpatientOutpatient- Treatment ≥8 years: 100 mg/dose PO bid PLUS Cefoxitin 25 mg/kg/dose IV q6h
Dose limit: 2 g/dose)- Ceftriaxone 250 mg IM as a single dose PLUS doxycycline 100 mg PO bid x 14 days
OR
2 mg/kg/dose PO q12h for 5-10 days depending on severity Dose limit: 100 mg/dose
TreatmentProphylaxis2 mg/kg/dose PO bid for 7 days Dose limit: 200 mg/day2 mg/kg/dose PO once daily Dose limit: 100 mg/day
Cutaneous Abscesses, Furuncles, Carbuncles, and Boils (with or without cellulitis):
Use Clindamycin or Doxycycline if Group A strep is strongly suspected despite the failure of 1st-line treatment
Tick Bites:
With long-term use, monitor BUN, hematologic, and hepatic function tests; observe for changes in bowel frequency
May be given with food
Food decreases GI side effects; take with a glass of water to avoid esophageal ulceration; avoid concomitant use of antacids or drugs containing aluminum, calcium, magnesium or iron
Not recommended for children less than 8 years old, with exception for circumstances when benefits outweigh risks
Intravenous doxycycline is not marketed in Canada; may be available through the Special Access Program (SAP)
