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Prolongation of QTc interval - Association with increased cardiovascular mortality in observational studies
Prolonged half life may contribute to macrolide resistance
While less risk of interaction compared to other macrolides, several potential CYP450 interactions may occur; consult a pharmacist for for more details
Avoid concurrent use with other drugs that prolong QTc
T 1/2: Infants and children 54.5 hours Excretion: Biliary (50% unchanged); urine (6-14% unchanged)