Meningitis
0-7 days post-natal age
67 mg/kg/dose IV q8h
>7 days post-natal age
75 mg/kg/dose IV q6h
Clinical Sepsis (non-meningitis)
<1.2 kg
50mg/kg/dose IV q12h
1.2-2 kg
- 0-7 days: 50mg/kg/dose IV q12h
- >7 days: 50mg/kg/dose IV q8h
>2 kg
- 0-7 days: 50mg/kg/dose IV q8h
- >7 days: 50mg/kg/dose IV q6h
Other Infections (e.g. UTI, Pneumonia)
<1.2 kg
25mg/kg/dose IV q12h
1.2-2 kg
- 0-7 days: 25mg/kg/dose IV q12h
- >7 days: 25mg/kg/dose IV q8h
>2 kg
- 0-7 days: 25mg/kg/dose IV q8h
- >7 days: 25mg/kg/dose IV q6h
UTI Prophylaxis (if unable to tolerate PO)
25mg/kg/dose IV q12h
