IV: $$

Spectrum of Activity

General Information

ODB funded

  • Allergy, rash
  • Non-allergic rash occurs in 5% to 10% of children and is a generalized dull red, maculopapular rash, generally appearing 3 to 14 days after the start of therapy
  • Rare: cytopenias, positive Coombs
  • With prolonged therapy, monitor renal, hepatic, and hematologic function periodically
  • Observe for change in bowel frequency
  • Observe for signs of anaphylaxis with first dose
  • Food decreases ampicillin absorption rate; may decrease ampicillin serum concentration.
  • Management: Take at equal intervals around-the-clock, preferably on an empty stomach (30 minutes before or 2 hours after meals). Maintain adequate hydration, unless instructed to restrict fluid intake.