Mild to moderate infections
35 mg/kg/dose IV/IM q8h Dose limit: 6 g/day (2 g/dose)
Severe infections
50 mg/kg/dose IV/IM q6h-q8h Dose limit: 12 g/day (4 g/dose)
Meningitis
50 mg/kg/dose IV/IM q6h (up to 75 mg/kg/dose may be used in selected cases in consultation with ID) Dose limit: 12 g/day
Sickle Cell Disease (meningitis not suspected)
50 mg/kg/dose IV q6h or 67 mg/kg/dose IV q8h Dose limit: 12 g/day
