Meningitis in children ≥1 month of age
OR
Dose limit: 2 g/dose, 4 g/day
Sepsis, severe pneumonia in ICU patients, sickle cell disease, osteomyelitis, and other severe infections
100 mg/kg/dose IV/IM q24h Dose limit: 2 g/day
Endocarditis
50 mg/kg/dose IV q12h
Dose limit: 2 g/dose; 4 g/day
Community-acquired pneumonia (non-severe), peritonitis, arthritis, bacteremia
50 mg/kg/dose IV/IM q24h Dose limit: 1 g/day
Appendicitis (perforated)
50mg/kg/dose IV q24h in combination with metronidazole Dose limit: 2g/day
Otitis Media
50mg/kg/dose IM daily x 1 to 3 days
Dose limit: 1 g/day
If symptoms persist after the first dose, additional doses are necessary. Patients should be followed up closely.
50mg/kg/dose IM daily x 3 days
Dose limit: 1 g/day
Uncomplicated Gonococcal Infection
50mg/kg IM Once Dose limit: 250mg/dose
