Antimicrobials
Aztreonam

Aztreonam

Medium
N/A

Dosing

General Information

Therapy of gram negative infections including Pseudomonas, particularly in patients with penicillin and cephalosporin allergy or when there is no alternative susceptible agent.

Nebulized form used in cystic fibrosis patients.

Empiric therapy for febrile neutropenia.

Monitor liver enzymes.

  • Elevated liver enzymes
  • Cytopenias
  • Eosinophilia
  • Phlebitis at injection site
  • Rash/allergy
  • CNS toxicity

No significant interactions.

Antimicrobial class: Monobactam

Pregnancy category: B

Average serum half life: 2 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

Biliary penetration: Moderate