Firstline - Clinical Decisions

Clinical Management & Treatment

Treatment of Mild-to-Moderate Illness (Outpatient)

Criteria

Patients not requiring supplementary oxygen

Treatment (follow links for details)

Supportive care

AND

Evaluate for Inhaled Budesonide

AND

Evaluate for Nirmatrelvir/Ritonavir (Paxlovid) Therapy

OR

Evaluate for 3-day Remdesivir Therapy (if NOT a candidate for Paxlovid)

AND

Other Treatment Considerations

Additional Information

Systemic corticosteroids (dexamethasone) NOT recommended

Antibiotic therapy NOT recommended