For most indications, azithromycin or clarithromycin are preferred
Motility agent
As part of a combination therapy for bowel preparation for colorectal surgery
Nausea/vomiting (25%)
Diarrhea (8%)
Prolonged QT interval and Torsades de Pointes
Substrate of CYP3A4. Multiple CYP450 interactions possible
Caution with QTc prolonging medications
May increase digoxin and carbemazepine levels
Statins: risk rhabdomyolysis
Monitor QTc in patients with increased risk.
250 mg TAB: $0.2
1 g (20 mL) VIAL: $30
500 mg (10 mL) VIAL: $18
Antimicrobial Class: Macrolide
Route of Elimination: Primarily hepatic
Adapted from the Horizon Health Network Antimicrobial Stewardship Program