Features of typical urticaria:
1) Central swelling with surrounding erythema (variable size) 2) Pruritus 3) Duration of individual lesions <24h
Urticaria
Photo credit: Allergy and Asthma Network https://allergyasthmanetwork.org/allergies/hives/
Features of typical angioedema:
1) Subcutaneous swelling with surrounding erythema 2) May or may not be itchy. Often accompanied by pain and tenderness. 3) Duration of lesions 24-48 hr
Angioedema
Photo credit: Usatine, R. (2009). The color atlas of family medicine. New York: McGraw-Hill Medical.
Features of typical maculopapular rashes:
1) Duration >24h 2) Consists of flat macules and raised papules 3) Starts in one area then spreads 4) Fine scaling or dry skin
Macular papular rash
Photo credit: Primary Care Dermatology Society
Severe systemic or cutaneous adverse drug reactions should be suspected for any patients with:
Lip involvement and desquamation in SJS
Photo Credit: Oscar Tamez-Rivera, Nataly Mercado and Amarante Gutiérrez-Martin
Pediatrics in Review May 2017, 38 (5) 234; DOI: https://doi.org/10.1542/pir.2015-0114
Vasculitis rash with target lesions
Vasculitic rash and desquamation with SJS
Conjunctivitis in SJS
Photo credit: Wang, JW, Rixen JJ, Goins KM, Kitzmann AS. Ocular Manifestations of Stevens-Johnson Syndrome: 13-year-old female with mucosal and dermatologic eruptions. EyeRounds.org. August 20, 2014; available from http://EyeRounds.org/cases/192-Stevens-Johnson.htm
Resolving vasculitic lesion
Generalized pustulosis
Guidelines
