Guidelines
EOS/GPS >2

EOS/GPS >2

Timing and Duration of Therapy

Initiate Ampicillin and Gentamicin immediately after admission (post blood culture)

Add Cloxacillin to antibiotic therpay within 60 mins prior to silo placement

Continue Ampicillin, Gentamicin, AND Cloxacillin while silo in situ (duration of Ampicillin is based upon need to cover EOS)

Antibiotics

PLUS

PLUS

  • Less than 30 weeks: 5 mg/kg/dose once
  • Greater than or equal to 30 weeks and/or less than or equal to 34 weeks: 4 mg/kg/dose q36h
  • Greater than 34 weeks: 4 mg/kg/dose q24h

Consult pharmacy for subsequent gentamicin doses and levels for patients less than 30 weeks

  • Pre and Post dose gentamicin levels around 2nd dose if treating greater than 48 hours