HBIG and Vaccine

Indications

For newborns if the:

  • Mother is a Hepatitis B carrier (HBsAg positive)

  • Mother is at high risk, i.e. IV substance use and/or sex trade worker (STW) for hepatitis B, but negative (possible window period) or unknown for HBsAg

For newborns when the:

  • Primary care giver or other household contact (e.g. father, nanny etc.) of infant has chronic hepatitis B virus infection

  • Mother is at high risk for Hepatitis B (other than IV substance use or STW) and her status is unknown or negative

  • Father or other primary caregiver is at high risk for Hepatitis B and their status is unknown or negative

Procedure

Physician/RM or Registered Nurse (RN)

Verify the woman’s Health Record contains confirmation of Hepatitis B Surface Antigen (HBsAg) status

  • Obtain from the primary care provider’s office or PHSA Provincial lab

  • Find this documentation in the woman’s prenatal records

Physician/RM (for woman who is eligible for HBIG)

Obtain the woman’s consent for blood product administration

  • The woman signs the Consent for Transfusion of Blood and/or Blood Products form for the newborn

RN: Administer medication in order - HBIG first, then the Hepatitis B Vaccine

1. HBIG

  • Newborn Site: Right Thigh

  • Administration Time: Within 1st hours of life

2. Vaccine

  • Newborn Site: Left Thigh

  • Administration Time: Within 1st hours of life

More Information

A Physician/ Registered Midwife’s written order is required for the administration of:

  • Hepatitis B Immune Globulin (HBIG)

  • Hepatitis B vaccine

Physicians/ Registered Midwife’s (RM) obtain Consent or Refusal for Transfusion of Blood and/or Blood Products from the parents of the newborn.

Applicability: Administration of Hepatitis B Immune Globulin and Hepatitis B vaccine occurs in the Acute Perinatal Program.

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