Infant of Mother with Unknown HIV Status

Infant of Mother with Unknown HIV Status


If HIV infection has not been ruled out: AVOID infant feeding of breast milk until MATERNAL HIV negative status is confirmed and ongoing risk factors are ruled out

Universal precautions for blood and body fluid

Wash injection site prior to IM injection or blood sampling

Initial Management

  • Self-identifies as at risk for HIV
  • Engaged in sex work
  • Injection drug use
  • Sex partner of person infected with HIV or using injection drugs
  • Sexually transmitted infection during pregnancy
  • From a population with a high prevalence of HIV
    • e.g. recent incarceration or from an HIV-endemic country


Additional Information

To be done within 90 MINUTES of birth

  • Complete blood count (CBC) with differential
  • Aspartate aminotransferase (AST)
  • Alanine aminotransferase (ALT)
  • Bilirubin, total unconjugated and conjugated
  • Urea
  • Creatinine (Cr), serum
  • Saliva swab CMV
  • Infant Diagnostic HIV PCR: Send 2mL in one EDTA tube (lavender top) (PHSA Lab Serology Screening Requisition #00073506 Request Infant Diagnostic HIV PCR under Other Tests)
  • Oak Tree Clinic staff (604-875-2250) are available to provide telephone advice Monday-Friday 08:30-16:30
  • After 16:30 and on weekends, contact BC Children's Hospital (604-875-2161) and ask for the Pediatric Infectious Disease specialist on call

Algorithm Overview

INFANT born to mother with unknown HIV status, or ongoing HIV risk since last HIV test: Initial management