Klebsiella pneumoniae

General Susceptibility

Usually susceptible to:

  • Cephalosporins including first generation

  • Aminoglycosides

  • TMP-SMX

  • Fluoroquinolones

  • Pip-Tazo

Almost always susceptible to:

  • Carbapenems

  • Aztreonam

  • Tigecycline

  • Colistin

Intrinsically resistant to ampicillin.

May be resistant to third generation cephalosporins (ESBLs), and rarely to carbapenems (carbapenemase enzymes).

Use fosfomycin and nitrofurantoin for UTI only, when confirmed susceptible

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