Cefepime

C difficile risk
High
Oral Bioavailability
N/A

Dosing

2 g IV q8 - 12h

0 - 10 eGFR10 - 30 eGFR30 - 60 eGFR60+ eGFR1g IV q24h2 g IV q24h2 g IV q12h2 g IV q8h

General Information

  • Broad spectrum antimicrobial with gram positive and gram negative coverage including Pseudomonas.

  • Used for nosocomial infections involving resistant organisms.

  • Empiric treatment of febrile neutropenia.

Pregnancy: Compatible.

Breastfeeding: Compatible.

  • Allergy (immediate & delayed)

  • Cytopenias

  • Positive direct Coombs test

  • Gastrointestinal intolerance

  • Transient increase in liver enzymes

Antimicrobial class: 4th generation Cephalosporin

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