Klebsiella pneumoniae (C&W Gram Negative)



General Information

Pregnancy: Compatible

Breastfeeding: Compatible

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria.

Used as part of the preterm prelabour rupture of membranes (PPROM) protocol.

Allergy and rash as for all beta-lactams. EBV related rash (not allergy).

Rare: cytopenias

  • Contraindicated in patients with true penicillin allergies.
  • Ampicillin shares a common structural side chain with cephalexin, therefore, there is an increased risk of allergy cross reaction between these agents.
    • Please refer to penicillin and beta lactam allergy management tool and cross reactivity table.

Antimicrobial class: aminopenicillin