Penicillin G Benzathine

Dosing

Not pregnant:Pregnant:2.4 million units IM x 1 dose2.4 million units IM weekly x 2 doses

Not pregnant:Pregnant:2.4 million units IM weekly x 3 doses2.4 million units IM weekly x 3 doses

50,000 units/kg IM x 1

Note: Not recommended for use in neonates with definitive congenital syphilis infection; penicillin G sodium is the agent of choice

IM

600,000 units/mL

Store in refrigerator Do not freeze

General Information

Treatment of syphilis (excluding neurosyphilis).

Pregnancy: Compatible.

Breastfeeding: Compatible.

Do not inject near an artery or a nerve; permanent neurological damage or gangrene may result. When doses are repeated, rotate the injection site. Do not administer IV, intra-arterially, or SubQ.

Allergic reaction

No significant drug interactions.

Long acting benzathine penicillin G is the appropriate treatment for syphilis. It achieves detectable serum levels of penicillin for 2 - 4 weeks and is required to adequately treat infectious syphilis. Short acting penicillin G does not provide adequate treatment for syphilis (except neurosyphilis).

Pregnant individuals with syphilis with a penicillin allergy should undergo desensitization.

Do not inject near an artery or a nerve; permanent neurological damage or gangrene may result. When doses are repeated, rotate the injection site. Do not administer IV, intra-arterially, or SubQ.

Antimicrobial class: Penicillin (long acting, see additional information)

Terms of Use | Feedback
© Copyright 2021 Spectrum Mobile Health Inc., dba Firstline Clinical. All rights reserved.