PICU, ID, Surgery, and/or relevant subspecialty team(s) if required
Assess need for emergent surgical source control with debridement of the affected area.
Before starting antimicrobial therapy, take blood/urine/CSF and/or other relevant samples for culture wherever possible.
Consider the need for dose adjustments (e.g. renal impairment) and age-related contraindications for antimicrobials.
PLUS
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As anti-MRSA agent (current local MRSA rates are available via the hospital antibiogram)
PLUS
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As anti-MRSA agent (current local MRSA rates are available via the hospital antibiogram)
Adjust treatment according to microbiologic results as soon as they become available.
The following factors have been associated with MRSA in previous studies: