Gram negative organisms, usually "SPICEM" (see additional information), that have a chromosomal beta-lactamase
Most AmpC organisms are nosocomially encountered, are GI flora and are part of the Enterobacteriaceae family
Cause syndromes by the organism that possesses AmpC (see individual organism)
ESBLs vs. ampC: Most ESBLs are plasmid-encoded, whereas ampCs are usually inducible and chromosomal
In the lab, ampCs test resistant to cefoxitin and cefotetan. They test susceptible to aztreonam
SPICEM stands for Serratia, Pseudomonas and Providencia, (Indole positive) Proteus vulgaris, Citrobacter, Enterobacter, and Morganella