Antimicrobials
Cephalexin

Cephalexin

Medium
Excellent
PO: $ tablet, $$ suspension

General Information

Uncomplicated skin and soft tissue infection, osteomyelitis, MSSA infections

  • Capsule: 250mg, 500mg
  • Suspension: 50 mg/mL

Neonatal:

  • Oral suspension: 250 mg/5 mL powder

More palatable, less GI upset and higher bioavailability than PO cloxacillin

Neonatal: Shake well before each use

Antimicrobial class: First generation cephalosporin - oral

Average serum half life:

  • Neonates: 5 hours
  • Children 3 to 12 months: 2.5 hours
  • Adults: 0.5-1.2 hours

Route of Elimination: >90% of dose excreted as unchanged drug in urine within 8 hours