Empiric therapy of bacterial meningitis, complicated community acquired pneumonia, nosocomial Gram negative infections (except Pseudomonas)
Due to the risk of ceftriaxone-calcium precipitates, which have caused serious cardiopulmonary events in infants, ceftriaxone must not be mixed or administered simultaneously with calcium containing IV solutions, including parenteral nutrition, neither co-administered nor via Y-site.
Neonatal Contraindications:
Antimicrobial class: Parenteral Cephalosporin - 3rd Generation
Average serum half life:
Route of Elimination: Unchanged in the urine (33-67%) by glomerular filtration and in feces via bile