Antimicrobials
Pentamidine

Pentamidine

Restricted

N/A
N/A
IV: $$$

General Information

  • Second-line for the treatment or prophylaxis of pneumocystis jirovecii pneumonia
  • May consider for patients who are intolerant to or fail co- trimoxazole

Adverse effects more common with treatment doses: 

  • Hypoglycemia
  • Nephrotoxicity
  • Hypotension
  • Increased liver enzymes
  • Leukopenia
  • Neutropenia
  • Thrombocytopenia

Cough and bronchospasm may occur with inhalation therapy. Pretreatment with bronchodilator may be beneficial.

Injection: 300 mg/vial