Guidelines
Candida Line Infection

Candida Line Infection

Note

  • ID consult required
  • Remove central lines

Initiate empiric treatment until ID and susceptibilities known

Empiric Treatment for Non-Neutropenic Patients

Critically ill:

OR

Non-critically ill and no prior azole exposure:

Empiric Treatment for Neutropenic Patients

Duration and De-escalation

Duration: 

  • Uncomplicated bacteremia (no metastatic complications): minimum 14 days from first negative culture
  • Complicated (e.g. endocarditis, osteomyelitis, unremovable source or bacteremia that persists more than 72 hours on appropriate therapy): requires 6 weeks of therapy

For all patients repeat blood cultures q48h until negative

Never considered a contaminant