Bacteremia - Central Line Associated
Enterococcus Species

Enterococcus Species

Empiric Regimen

  • Order set link found in vancomycin monograph
  • Notify pharmacist for levels and further dosing

Once Susceptibilities Known

1st line, if susceptible and no allergy

OR

2nd line, if allergy or resistance

Vancomycin Resistant Enterococci (VRE)

Clinical Considerations

Duration:

  • Uncomplicated (removable source): minimum 2 weeks from first negative blood culture
  • Complicated (e.g. endocarditis, osteomyelitis, unremovable source or bacteremia that persists more than 72 hours on appropriate therapy): requires 6 weeks of therapy