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Guidelines
Staphylococcus aureus

Staphylococcus aureus

Note

  • ID consult required
  • Remove central lines

Empiric Treatment

Continue with vancomycin + cloxacillin/cefazolin until susceptibilities known

Vancomycin as per order set 10-111-5335: Initiation of Vancomycin for Adult Inpatients
​
  • Order set link found in vancomycin monograph
  • Notify pharmacist for levels and further dosing

PLUS ONE OF

OR

Duration and De-escalation

Duration: 

  • Uncomplicated (removable source): minimum 2 weeks from first negative blood culture
  • Complicated (e.g. endocarditis, osteomyelitis, unremovable source or bacteremia that persists more than 72 hours on appropriate therapy): requires 6 weeks of therapy