Guidelines
Clostridium Difficile Infection (CDI)

Clostridium Difficile Infection (CDI)

Clinical Key Points

DISCONTINUE current antibiotics if possible

DISCONTINUE anti-peristaltics, laxatives, pro-motility agents, anti-inflammatories (NSAIDs)

If present, REASSESS need for Proton Pump Inhibitor or Histamine-2 Receptor Antagonist

CDI Severity

WBC less than 15 and SrCr less than or equal to 1.5 x baseline

WBC greater than 15, or acute kidney injury (SrCr greater than 1.5 x baseline), or hypoalbuminemia

Toxic megacolon, perforation, ileus, sepsis/hypotension, shock or peritonitis

More Information

Order set: 10-111-5354