Antimicrobials
Pyrazinamide

Pyrazinamide

Dosing

General Information

Treatment of tuberculosis in combination with other anti-tubercular drugs

  • Periodic liver function tests
  • Serum uric acid
  • Chest x-ray 2-3 months into treatment and at completion
  • Malaise

  • Anorexia

  • Nausea/vomiting

  • Arthralgia, myalgia

  • Avoid use following BCG and or Cholera vaccine

  • May increase levels of rifampin

  • May decrease levels of cyclosporine, typhoid vaccine