Antimicrobials
Micafungin

Micafungin

Restricted

Low
N/A

Spectrum of Activity

General Information

Restricted to 2nd line use after fluconazole.

FDA Treatment Indications: Therapy of suspected and confirmed invasive fungal infections such as candidemia, disseminated candidiasis, candida abscess & peritonitis infection.

  • Increased liver enzymes
  • GI upset

Increases levels of sirolimus and nifedipine (mild).

Restricted to fungal infections that are known or suspected to be resistant to fluconazole or in patients intolerant to fluconazole.

Antimicrobial class: Echinocandin

Pregnancy category: C

Average serum half life: 15 hours

Urine penetration: Poor

Lung penetration: Therapeutic

CSF penetration: Poor

Biliary penetration: Therapeutic