Nirmatrelvir/Ritonavir (PAXLOVID) for Mild-to-Moderate Illness
Nirmatrelvir/Ritonavir(PAXLOVID) Eligibility Algorithm & Risk Calculator

Nirmatrelvir/Ritonavir(PAXLOVID) Eligibility Algorithm & Risk Calculator

Background

  • For community-based treatment, the eligibility form (see below) must be completed and sent to the pharmacy along with the prescription
  • Eligibility form is NOT required for patients admitted to hospital

Treatment algorithm and risk calculator may be used to guide treatment decisions but should not be used as a substitute for clinical judgement.

Nirmatrelvir/ritonavir Eligibility Algorithm and Risk Calculator

To initiate algorithm, select boxes that apply:

  • Clinical signs of pneumonia (fever, cough, dyspnea, tachypnea) may or may not be present; 
  • No signs of severe pneumonia (i.e. respiratory rate > 30 breaths/min, SpO2 ≤ 92% on room air, severe respiratory distress (ex. breathlessness at rest; talks in words only and not sentences or phrases))
  • Patient NOT requiring supplementary or additional oxygen.

Adapted from the Horizon Health Network Antimicrobial Stewardship Program