Streptococcus pyogenes, Group A

Streptococcus pyogenes, Group A


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General Information

Gram positive cocci in chains, beta-hemolytic

Reservoir is human skin and oropharynx/mucous membranes.

Person-to-person transmission.

Occasionally foodborne.

Most common manifestations are:

  • Tonsillopharyngitis ("Strep throat")
  • Skin infections (impetigo, erysipelas, cellulitis)

Other invasive infections:

  • Bacteremia
  • Endocarditis
  • Necrotizing soft tissue infections
  • Meningitis
  • Toxic shock syndrome
  • Pneumonia
  • Other sterile space infections

Causative agent of scarlet fever.

Nonsuppurative complications include post streptococcal glomerulonephritis and acute rheumatic fever.

Contact and droplet precautions for invasive disease for the first 24hrs of antimicrobial therapy

Post-exposure prophylaxis may be indicated.