Remdesivir
Adult

Adult

Age 12 years and older with a body weight of at least 40 kg

Mild-to-moderate illness (i.e. NOT requiring supplemental oxygen)

Remdesivir 200 mg IV x 1 on day 1, then 100 mg IV q24h x 2 days.

Severe illness (i.e. requiring low-flow supplemental oxygen)

200 mg IV x 1 loading dose on day 1, then 100 mg IV q24h for 4 days or until hospital discharge, whichever comes first.

Duration of therapy if not improving after 5 days

  • There is insufficient data on the optimal duration of remdesivir for patients with COVID-19 who have not shown clinical improvement after 5 days of therapy.

  • Depending on clinical judgement and availability, some may consider extending the duration of therapy to a maximum of 10 days.