Vancomycin PO

Vancomycin PO


Spectrum of Activity


General Information

  • C. difficile infection only, no oral absorption, so not useful for other infections.

  • Do not use oral vancomycin as step-down therapy for IV vancomycin

Possibility of accumulation in severe renal dysfunction and fulminant colitis.

  • GI upset
  • Nausea
  • Poor taste (when used as oral solution)

No oral absorption.

May increase vancomycin resistant Enterococcus colonization in the gut.

Antimicrobial class: Glycopeptide

Pregnancy category: B

Average serum half life: 0 hours

Urine penetration: None

Lung penetration: None

CSF penetration: None

Biliary penetration: None