Note
Dosing based on IBW, unless actual body weight greater than 20% above IBW, then use dosing weight
Not On Dialysis
Note: For Gram positive infections only; tobramycin should not be used for synergy against Enterococcus spp infections (use gentamicin)
Intermittent Hemodialysis (IHD)
1 mg/kg IV at the end of each dialysis session Dose adjustments based on pre-dialysis levels (dosing based on patient's dry weight if not obese; if dry weight is greater than 20% above IBW, then use dosing weight)