Oseltamivir
Renal

Renal

Not On Dialysis

CrCl 30-60
  • Treatment: 30mg PO q12h for 5 days
  • Prophylaxis: 30mg PO q24h for 10-14 days
CrCl 10-29
  • Treatment: 30mg PO q24h for 5 days
  • Prophylaxis: 30mg PO q2days for 10-14 days
CrCl <10
  • Treatment: 75mg PO ONCE (Use with caution)
  • Prophylaxis: 30mg PO ONCE (Use with caution)

Intermittent Hemodialysis (IHD)

Treatment

75mg PO after each dialysis session over a period of 5 days

Prophylaxis

An initial 30mg PO dose may be given prior to HD if exposed during the 48 hours between dialysis sessions

Then administer 30mg PO after alternate dialysis sessions over a period of 10-14 days