Imipenem+Cilastatin
Renal

Renal

Note

Meropenem preferred for CNS infections and when CrCl <30 mL/min

Not On Dialysis

CrCl 31-49

500mg IV q6-8h

CrCl 21-30

500mg IV q8-12h

CrCl <20

250-500mg IV q12h

Intermittent Hemodialysis (IHD)

250-500mg IV q12h

Administer dose after dialysis on dialysis days