Antimicrobials
Fosfomycin

Fosfomycin

Low
Moderate

Spectrum of Activity

Dosing

General Information

Uncomplicated Urinary Tract Infection/Acute cystitis, especially involving ESBL producing organisms

Off-label

  • Prostatitis (different dose)

DO NOT use for upper urinary tract infections (pyelonephritis or renal abscess) or systemic infections (bacteremia)

  •  GI upset, especially diarrhea
  •  Headache
  •  Eosinophilia, neutropenia

No significant interactions

Antimicrobial class: Phosphonic acid derivative

Pregnancy category: B

Average serum half life: 6 hours

Urine penetration: Therapeutic