Antimicrobials
Amoxicillin+Clavulanate

Amoxicillin+Clavulanate

High
Excellent

Dosing

General Information

Prophylaxis and treatment of human and animal bite wounds.

Polymicrobial infections involving the respiratory tract or abdomen.

For prolonged therapy, monitor liver enzymes and function.

  •  Allergy/rash (immediate or delayed)
  •  Note EBV related rash
  •  Cytopenias
  •  Diarrhea (less likely with twice daily dosing regimen using 875 mg tab)
  • C. difficile
  •  Hepatotoxicity due to clavulinate - usually mild, liver failure is rare.

Increased risk of rash with allopurinol

Antimicrobial class: Aminopenicillin + Beta-lactamase inhibitor

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic

Biliary penetration: Therapeutic