Monitor creatinine at least 3 times/week. Discontinue if any signs of vestibular or ototoxicity.
All aminoglycosides carry potential for cochlear, renal and vestibulotoxicity. If considering using amikacin, strongly consider ID consultation.
For conventional dosing: Target Peak 20-30 mg/L, Trough <4 mg/L. Peak levels usually not required but if drawn, record time of dose and time of level draw as accurately as possible.
Consult pharmacist for level interpretation and dose individualization
For once daily dosing: Target Trough <4 mg/L. Peak levels not recommended.