Penicillin VK

Penicillin VK

C difficile risk
Oral Bioavailability


250-500mg PO q6h

CrCl less than 10 mL/min250-500mg PO q8h

General Information

Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract).

Prophylaxis after rheumatic fever.

  •  Monitor for allergy.

  •  Periodic CBC, SCr

  • Allergy (anaphylaxis) and other rash

  • Cytopenias, Positive Coombs, Eosinophilia

  • Serum sickness

  • AIN

No significant interactions

Antimicrobial class: Penicillin

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic