Anaerobic infections above the diaphragm, especially dental infection.
Severe Gram positive skin and soft tissue infections including necrotizing fasciitis as an adjunctive agent to a beta lactam for reducing toxin production.
Skin & soft tissue infections involving susceptible MRSA. Do not use empirically for SSTI due to increased resistance of staphylococcal species to clindamycin (see antibiogram).
Susceptible infections and surgical prophylaxis in setting of IgE mediated beta-lactam allergy, when cefazolin or vancomycin is not an option.
For decreasing toxin production in toxic shock syndrome.
High Risk of clostridium difficile infection
Antimicrobial class: Lincosamide
Pregnancy category: B
Average serum half life: 2.4 hours
Urine penetration: Poor
Lung penetration: Therapeutic
CSF penetration: Poor
Biliary penetration: Therapeutic