Antimicrobials
Caspofungin

Caspofungin

Restricted

Low
N/A

Spectrum of Activity

General Information

Caspofungin is often used in management of suspected and confirmed invasive fungal infections, particularly Candidiasis and Aspergillosis

  • Liver enzymes at baseline and every 1-2 weeks
  • Infusion-related reactions (rash, pruritis)
  • Phlebitis
  • Headache
  • Nausea and vomiting
  • Elevations in hepatic enzymes

Caspofungin has poor vitreous, CNS and urinary penetration. It should not be used for treatment of Candida urinary tract infections.

Use must be approved by Infectious Diseases.

Antimicrobial class: Echinocandin

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Poor