25-50 mg/kg/DAY divided q6-8h. Max 1 g/DOSE.
100 to 150 mg/kg/DAY divided q6h. Max 1 g/DOSE.
Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
Uncomplicated skin and soft tissue infection, MSSA infections
Allergy/rash (immediate or delayed).
Can cause positive Coombs, cytopenias, eosinophilia.
Antimicrobial class: First generation cephalosporin - oral
Average serum half life:
Neonates: 5 hours.
Children 3 to 12 months: 2.5 hours.
Adults: 0.5-1.2 hours
Route of Elimination: 80% to 100% of dose excreted as unchanged drug in urine within 8 hours